Plymouth reclaimed top spot in League Two last Saturday and will look to build on that with a Boxing Day clash at home against struggling Yeovil.
Argyle ended a four-game winless run with a 2-1 victory at Hartlepool, which saw them retake first on goal difference.
A massive 30 points behind their opponents, Yeovil are in 23rd place on 13 points and have collected just six of those on their travels.
The Glovers desperately need to close the gap to those above or face a third consecutive relegation, but this time it will be out of the Football League.
Joint top on 43 points are Northampton, who have an inferior goal difference to the Green Army.
A 2-1 defeat to Portsmouth last weekend was labelled “scandalous” by Town boss Chris Wilder, which ended an eight-game unbeaten run.
The Cobblers will want to get back to winnings ways as they visit York, who are at the other end of the table.
City secured their first victory in over two months as they beat Morecambe 2-1 last week, moving them two points clear of the relegation zone.
Condemned to the foot of the Football League are Dagenham and Redbridge, who this week sacked Wayne Burnett after just one win in 16 games.
On 13 points, the club are yet to win at home this season and have collected a shocking four points; relegation form in any division.
They will hope to deliver a delayed Christmas present to their fans as they host Cambridge on Saturday.
United are unbeaten in four and are six points off the play-offs after an upturn in form since Shaun Derry replaced Richard Money at the helm.
Oxford dropped to third with a 2-1 loss to Wycombe at the weekend, two points behind Argyle.
The U’s, who announced that CEO Mark Ashton will be leaving the Kassam Stadium, with majority shareholder Darryl Eales taking on the role, will need to keep the pressure on the two clubs above if they have a desire to remain in the automatic promotion place.
Exeter are the visitors and, after a last gasp 3-2 defeat against managerless Luton last week, they will want to put things right.
The Grecians are also buoyed with a televised home match against Liverpool on January 8, making a busy period even more vital.
Portsmouth closed the gap between the top-four to just three points, after their victory at Northampton.
Pompey are unbeaten in six with three wins, and are now within touching distance of the automatic promotion places.
Leyton Oreint are their hosts and are unbeaten in five, the last four beings draws.
Orient’s average form has seen them fall out of the top-seven to 10th, but they are still just three points away from seventh-placed Bristol Rovers.
Carlisle United, who have to play away from Brunton Park due to the terrible flooding in the area, are unbeaten in five and are fifth.
The Cumbrians will want to continue their good form when they travel to take on Accrington.
Stanley are just a point behind their opponents in sixth, and, after boss John Coleman said the Football League are favouring their opponents by letting them play elsewhere, the two clubs will have the chance to sort their differences out at the Crown Ground.
Newport have only lost once in their last nine, finding themselves seven points and three places clear of the drop.
Taking 12 points on their travels, County, who make the trip to Barnet, will want to stay a comfortable distance ahead of the bottom-two.
The Bees, who are five points and a single place ahead of their visitors, have taken an impressive 20 points at home.
All League Two Matches:
Accrington vs Carlisle
Barnet vs Newport
Crawley vs Stevenage
Dag & Red vs Cambridge
Hartlepool vs Notts County
Leyton Orient vs Portsmouth
Luton vs Wycombe
Morecambe vs Manfield
Oxford Utd vs Exeter
Plymouth vs Yeovil
Wimbledon vs Bristol Rovers
York vs Northampton